Buy Arimidex Online

Active Ingredient: Anastrozole

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Arimidex: composition, indications, dosage, side effects

Arimidex is a hormonal antitumor agent, the therapeutic effect of which is due to the properties of the active component-anastrozole. It is prescribed for women with breast tumors. Due to the therapy, there is a significant decrease in the level of estradiol. The drug has a good pharmacological profile – anastrozole is completely absorbed in the gastrointestinal tract, quickly creating a therapeutic concentration. Progestogenic, estrogenic and androgenic activity of the drug does not show. The use of Arimidex in pediatrics is contraindicated. Take the drug in the presence of confirmed hypersensitivity to the components, against the background of severe violations of liver and kidney function can not be. Arimidex is prescribed in a standard dose (including elderly women) - 1 mg per day. The duration of therapy is determined by the progression of symptoms and tolerability. Side effects that occur against the background of taking the drug, usually manifest themselves easily and are reversible. Most often, women reported asthenia, arthritis, digestive disorders, vaginal bleeding, hypercholesterolemia, bone pain, allergic reactions, and drowsiness.

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It is most likely that a tumor in the breast is cancer
80% of the tumors found in the breast are not malignant. Most often there are cysts or benign formations. There are also transient seals of breast tissue associated, as a rule, with the menstrual cycle. It is impossible to determine the nature of education based only on the data of an independent survey. If you determine any deviation from the norm, it is important to immediately consult a doctor.
If a tumor is detected, however, mammography is normal, there is no need for further research
Mammography itself is not a completely accurate diagnostic method. Most often, this study is combined with others, such as ultrasound and MRI. The purpose of these studies is to exclude a tumor that was not detected at the first check. Based on the findings on additional images, the doctor will decide on further actions: a biopsy or observation.

How Arimidex Works

It is an aromatase hormone antagonist. During the postmenopausal period, estradiol is produced by converting androstenedione to estrone in peripheral tissues under the action of the aromatase enzyme. Next, estrone is converted to estradiol. The active substance of the drug blocks this process. This reduces the level of estradiol, which is necessary in the treatment of breast cancer. In postmenopausal women, the drug at a dose of 1 mg/day causes a decrease in the level of estradiol by 80%. It has no progestogenic or androgenic activity; at a dose of up to 10 mg / day, it does not affect the secretion of aldosterone and cortisol.

Composition and form of release

- Active ingredient: Anastrozole (1 mg).

- Arimidex is available in the form of tablets.

Arimidex Indications

Arimidex is used to treat advanced breast cancer in postmenopausal women (with positive indicators of hormone receptors).

Contraindications Arimidex

Arimidex is not used:

  • With intolerance to anastrozole, auxiliary components;
  • During pregnancy, breast-feeding;
  • Children.
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Breast cancer never causes pain
This is an inaccurate statement. Despite the fact that breast cancer in the early stages does not always cause discomfort and pain, an inflammatory form of breast cancer is also possible, which is often accompanied by pain, redness, local fever and soft tissue edema.
If a lump in the breast is detected during breast-feeding, it can't be cancer
Despite the fact that breastfeeding reduces the risk of developing breast cancer, it is impossible to completely eliminate the probability of occurrence of the disease. If a seal is detected during feeding, do not neglect to visit a specialist. Even in the period of breast-feeding can be safe to undergo ultrasound examination to exclude a malignant tumor.

Method of administration and dosage

Arimidex is used orally.

The recommended dose is 1 mg (one tablet) once a day.

In the early stages of invasive breast cancer (with positive hormone receptor values) in postmenopausal patients, the standard duration of adjuvant endocrine therapy is five years.

Patients with mild / moderate renal dysfunction do not need a dose adjustment. The use of the drug in this group of patients requires caution.

Patients with mild / moderate liver dysfunction do not need a dose adjustment. The use of the drug in this group of patients requires caution.

Use during pregnancy and lactation - Forbidden.

Overdose

In animal studies, the drug has demonstrated low toxicity. Possible increase in adverse reactions.

In case of overdose, symptomatic, supportive therapy is performed. It is necessary to monitor vital signs, carefully monitor the patient. Dialysis may be performed.

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In young women, a tumor in the breast can't be cancer
This statement is absolutely incorrect. Cancer can develop at any age, therefore, the detection of any seals requires contacting a doctor. Despite the fact that most patients with breast cancer are older than 50 years, the disease is often found at a younger age.
Large formations are more likely to be malignant
Breast tumors can achieve a variety of sizes. The size of neoplasms does not affect the probability of a malignant process. Often there are small-sized foci of particularly aggressive forms of breast cancer. If a new seal or changes in a previously known benign tumor are detected, even if these formations are small in size, an immediate examination is necessary.
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If a breast tumor is detected after a recent mammogram, you can safely wait a year until the next examination
As already explained above, mammography itself is not a completely accurate diagnostic method. If you have identified a tumor during self-examination, even after a recent mammogram, you should immediately consult a doctor.
If there was no breast cancer in family members, then most likely the tumor is benign
Many women believe that they are not at risk of developing breast cancer just because the disease has not occurred in their family members. This statement is erroneous. Only less than 15 % of women diagnosed with breast cancer have a family history of the disease. Therefore, it is necessary to examine every detected and suspected cancer tumor.

Side Effects

Digestive disorders: Anorexia, hypercholesterolemia, hypercalcemia, nausea, diarrhea.

Hepatobiliary disorders: Hepatitis, increased levels of alkaline phosphatase, AsAT, AlAT, gamma-glutamyltransferase, bilirubin.

Neurological disorders: Headache, carpal tunnel syndrome, drowsiness, sensitivity disorders (paresthesia, loss of taste, changes in taste sensations).

Cardiovascular disorders: Hot flashes.

Allergic reactions: Allergic reactions (chills, chest pain, trembling, urticaria, skin rash), anaphylaxis (manifested by shortness of breath, hypotension, cardiac arrest), dermatitis.

Dermatological disorders: Exanthema, hair thinning, alopecia, erythema polymorph, cutaneous vasculitis, Schenlein-Henoch purpura, Stevens — Johnson syndrome.

Musculoskeletal disorders: Arthralgia, arthritis, impaired joint mobility, osteoporosis, bone pain, myalgia, snapping finger syndrome.

Urogenital disorders: Vaginal bleeding, vaginal dryness.

General: Asthenia.

Storage Conditions and Terms

Arimidex must be stored in its original packaging in a place protected from direct sunlight, moisture, for no more than 5 years.

It is forbidden to use after the expiration date indicated on the package.

Recommended storage temperature: up to +30 °C.

Parents are obliged to ensure the safety of their children, excluding the possibility of their access to the medicine.